A Novel Perspective on Tubular C4d Positivity in BK Polyomavirus Nephropathy

A Novel Perspective on Tubular C4d Positivity in BK Polyomavirus Nephropathy

Introduction: Tubular basement membrane (TBM) C4d staining has been frequently observed in BK polyomavirus nephropathy (BKPyVN); however, its specificity and clinical implications remain unclear. Methods: Biopsy data from 272 patients with BK viruria, including 4 native BKPyVN, 150 allograft BKPyVN,...

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Main Authors: Tong Wu, Fangzhou Guo, Shicong Yang, Zeying Jiang, Xianghong He, Qihua Wang, Zhixin Huang, Jue Wang, Zhenyu Xu, Meiyi Song, Xiaotao Hou, Gang Huang, Wenfang Chen
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Kidney International Reports
Subjects:
BK polyomavirus nephropathy
C4d
tubular basement membrane
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925002931
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