Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung.

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung.

To gain a better understanding of the transcriptional response of Aspergillus fumigatus during invasive pulmonary infection, we used a NanoString nCounter to assess the transcript levels of 467 A. fumigatus genes during growth in the lungs of immunosuppressed mice. These genes included ones known to...

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Main Authors: Hong Liu, Wenjie Xu, Vincent M Bruno, Quynh T Phan, Norma V Solis, Carol A Woolford, Rachel L Ehrlich, Amol C Shetty, Carrie McCraken, Jianfeng Lin, Michael J Bromley, Aaron P Mitchell, Scott G Filler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009235&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009235&type=printable

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