Connecting the Dots: NLRP3 Inflammasome as a Key Mediator in the Intersection of Depression and Cardiovascular Disease – A Narrative Review

Connecting the Dots: NLRP3 Inflammasome as a Key Mediator in the Intersection of Depression and Cardiovascular Disease – A Narrative Review

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide and frequently coexist with depressive disorders. The consequence of their concurrence is the exacerbation of both conditions. Numerous studies seek to understand the pathophysiological connection between this mental disorde...

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Bibliographic Details
Main Authors: Ghazaleh Ghaffaripour Jahromi, Nima Rezaei
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Heart and Mind
Subjects:
cardiovascular diseases
depression
etiology
heart–brain axis
mind–body connection
neuroinflammation
nucleotide-binding oligomerization domain-
leucine-rich repeat-
and pyrin domain-containing protein 3 inflammasome
psychocardiology
Online Access:https://journals.lww.com/10.4103/hm.HM-D-24-00076
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https://journals.lww.com/10.4103/hm.HM-D-24-00076

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