Endothelial cells nurture stem cell-like characteristics of osteosarcoma cells in a perivascular niche by CXCL12/CXCR4 pathway

Endothelial cells nurture stem cell-like characteristics of osteosarcoma cells in a perivascular niche by CXCL12/CXCR4 pathway

Objective‍　‍To investigate the effect of endothelial cells in the perivascular niche on the stem cell-like characteristics of osteosarcoma cells and primarily explore the possible molecular mechanism. Methods‍　‍A co-culture model was established in vitro using SV40T- human umbilical vein endothelial...

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Bibliographic Details
Main Authors: CAO Ya, LIU Yang, WANG Yang
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-07-01
Series:陆军军医大学学报
Subjects:
‍perivascular niche
endothelial cells
osteosarcoma stem cells
c-x-c chemokine receptor type 4
Online Access:https://aammt.tmmu.edu.cn/html/202505024.html
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