Analysis of zebrafish homologs within the human genome provides valuable insights into exploring pan-cancer alternative splicing events as prognostic markers and therapeutic targets

Alternative splicing (AS) is pivotal in gene expression regulation and protein diversity generation. Suppression of aberrant AS holds promise in cancer management. Utilizing zebrafish-human homologous genes, we investigated AS events across 33 tumor types from TCGA, employing Cox regression analyses...

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Bibliographic Details
Main Authors: Yanjun Liang, Xiao Zhu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Medicine in Omics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590124925000069
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