Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study
ABSTRACT Background and Aims The recently approved maternal vaccination against respiratory syncytial virus (RSV) can reduce its burden among infants. However, vaccine hesitancy/resistance can undermine the beneficial impact of RSV vaccination. The aim of this study was to assess the willingness of...
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Wiley
2025-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.70319 |
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| author | Malik Sallam Tleen Kherfan Amwaj Al‐Farajat Leen Nemrawi Nada Atawneh Rand Fram Ala'a B. Al‐Tammemi Muna Barakat Kamil Fram |
| author_facet | Malik Sallam Tleen Kherfan Amwaj Al‐Farajat Leen Nemrawi Nada Atawneh Rand Fram Ala'a B. Al‐Tammemi Muna Barakat Kamil Fram |
| author_sort | Malik Sallam |
| collection | DOAJ |
| description | ABSTRACT Background and Aims The recently approved maternal vaccination against respiratory syncytial virus (RSV) can reduce its burden among infants. However, vaccine hesitancy/resistance can undermine the beneficial impact of RSV vaccination. The aim of this study was to assess the willingness of pregnant women in Jordan to receive RSV vaccination and its associated determinants. Methods Face‐to‐face interviews were conducted in obstetrics/gynecology clinics in the Central, Northern, and Southern regions of Jordan during January–February 2024, using a convenience sampling approach. Attitude to RSV vaccination was assessed using the previously validated ABCDEF scale. Results A total of 404 pregnant women participated in the study with a mean age of 30.1 ± 6.2 years. A majority of the participants showed willingness to receive RSV vaccination (n = 313, 77.5%), with hesitancy among 25 participants (6.2%), and resistance among 66 participants (16.3%). Variables that were significantly associated with a higher RSV vaccine acceptance in multivariate analysis were: age < 30 years (adjusted odds ratio (aOR): 2.45, p = 0.010), undergraduates (aOR: 3.27, p = 0.026), being a healthcare worker (aOR: 4.50, p = 0.036), and the history of previous COVID‐19/influenza vaccine uptake (aOR: 2.47, p = 0.045). Two out of the six ABCDEF constructs were significantly associated with RSV vaccine acceptance, namely the “Advice” construct (aOR: 10.38, p < 0.001) and the “Fear” construct (aOR: 21.49, p < 0.001). Conclusion This study highlighted the complex nature of attitude towards maternal RSV vaccination among pregnant women. The study showed the role of demographic variables, prior vaccination experience, trust in credible health institutions and vaccine safety, and the fear of RSV disease consequences in infants in shaping maternal attitude to RSV vaccination. Addressing these factors can help to effectively promote RSV vaccine uptake among pregnant women, subsequently helping to protect infants from the significant RSV disease burden. |
| format | Article |
| id | doaj-art-945bd51ef8b74f30bdbb501adc848d6b |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj-art-945bd51ef8b74f30bdbb501adc848d6b2025-01-29T03:42:40ZengWileyHealth Science Reports2398-88352025-01-0181n/an/a10.1002/hsr2.70319Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey StudyMalik Sallam0Tleen Kherfan1Amwaj Al‐Farajat2Leen Nemrawi3Nada Atawneh4Rand Fram5Ala'a B. Al‐Tammemi6Muna Barakat7Kamil Fram8Department of Pathology, Microbiology and Forensic Medicine, School of Medicine The University of Jordan Amman JordanDepartment of Pathology, Microbiology and Forensic Medicine, School of Medicine The University of Jordan Amman JordanJordan University Hospital Amman JordanJordan University Hospital Amman JordanSchool of Medicine The University of Jordan Amman JordanSchool of Medicine The University of Jordan Amman JordanResearch, Policy and Training Directorate, Jordan Center for Disease Control Amman JordanDepartment of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy Applied Science Private University Amman JordanDepartment of Obstetrics & Gynecology, School of Medicine The University of Jordan Amman JordanABSTRACT Background and Aims The recently approved maternal vaccination against respiratory syncytial virus (RSV) can reduce its burden among infants. However, vaccine hesitancy/resistance can undermine the beneficial impact of RSV vaccination. The aim of this study was to assess the willingness of pregnant women in Jordan to receive RSV vaccination and its associated determinants. Methods Face‐to‐face interviews were conducted in obstetrics/gynecology clinics in the Central, Northern, and Southern regions of Jordan during January–February 2024, using a convenience sampling approach. Attitude to RSV vaccination was assessed using the previously validated ABCDEF scale. Results A total of 404 pregnant women participated in the study with a mean age of 30.1 ± 6.2 years. A majority of the participants showed willingness to receive RSV vaccination (n = 313, 77.5%), with hesitancy among 25 participants (6.2%), and resistance among 66 participants (16.3%). Variables that were significantly associated with a higher RSV vaccine acceptance in multivariate analysis were: age < 30 years (adjusted odds ratio (aOR): 2.45, p = 0.010), undergraduates (aOR: 3.27, p = 0.026), being a healthcare worker (aOR: 4.50, p = 0.036), and the history of previous COVID‐19/influenza vaccine uptake (aOR: 2.47, p = 0.045). Two out of the six ABCDEF constructs were significantly associated with RSV vaccine acceptance, namely the “Advice” construct (aOR: 10.38, p < 0.001) and the “Fear” construct (aOR: 21.49, p < 0.001). Conclusion This study highlighted the complex nature of attitude towards maternal RSV vaccination among pregnant women. The study showed the role of demographic variables, prior vaccination experience, trust in credible health institutions and vaccine safety, and the fear of RSV disease consequences in infants in shaping maternal attitude to RSV vaccination. Addressing these factors can help to effectively promote RSV vaccine uptake among pregnant women, subsequently helping to protect infants from the significant RSV disease burden.https://doi.org/10.1002/hsr2.70319maternal immunizationpregnancyvaccine attitudevaccine hesitancy |
| spellingShingle | Malik Sallam Tleen Kherfan Amwaj Al‐Farajat Leen Nemrawi Nada Atawneh Rand Fram Ala'a B. Al‐Tammemi Muna Barakat Kamil Fram Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study Health Science Reports maternal immunization pregnancy vaccine attitude vaccine hesitancy |
| title | Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study |
| title_full | Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study |
| title_fullStr | Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study |
| title_full_unstemmed | Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study |
| title_short | Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study |
| title_sort | attitude to rsv vaccination among a cohort of pregnant women in jordan a cross sectional survey study |
| topic | maternal immunization pregnancy vaccine attitude vaccine hesitancy |
| url | https://doi.org/10.1002/hsr2.70319 |
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