Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey

The diagnosis of new variants and monitoring their potential effects on diagnosis, therapeutics, and vaccines by genomic sequencing is essential to manage global public crises. In the current study, spike-genome next-generation sequencing was generated from 492 SARS-CoV-2 isolates to evaluate the mu...

Full description

Saved in:
Bibliographic Details
Main Authors: Murat Sayan, Ayse Arikan, Murat Isbilen
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2022/4677720
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832562418974195712
author Murat Sayan
Ayse Arikan
Murat Isbilen
author_facet Murat Sayan
Ayse Arikan
Murat Isbilen
author_sort Murat Sayan
collection DOAJ
description The diagnosis of new variants and monitoring their potential effects on diagnosis, therapeutics, and vaccines by genomic sequencing is essential to manage global public crises. In the current study, spike-genome next-generation sequencing was generated from 492 SARS-CoV-2 isolates to evaluate the mutations in Turkey from April 2021 to February 2022. The variant analysis was performed using (Coronavirus Antiviral and Resistance Database (CoV-RDB) by Stanford University). We revealed that the lineages Alpha (B.1.1.7), Beta (B.1.351), Delta (B.1.617.2), Eta (B.1.525), variant of interest (VOI), lota (B.1.526), Zeta (P.2), Omicron (B.1.1.529), and Omicron BA.1 (B.1.1.529.1) were in the circulation in Turkey during the given period. The most common lineages were B.1.1.7, B.1.617.2, B.1.1.529, and B.1.1.529.1 SARS-CoV-2 variant circulation in Turkey seems highly heterogenetic; however, quite similar to the global epidemiologic analysis. The existence of globally circulating variants in the same chronological order in Turkey can be a guide for precautions, treatment, and vaccine options to be taken in the future.
format Article
id doaj-art-944de415da39478eb3f290da04e5a6d0
institution Kabale University
issn 1918-1493
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-944de415da39478eb3f290da04e5a6d02025-02-03T01:22:41ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932022-01-01202210.1155/2022/4677720Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in TurkeyMurat Sayan0Ayse Arikan1Murat Isbilen2Kocaeli UniversityNear East UniversityAcibadem Mehmet Ali Aydinlar UniversityThe diagnosis of new variants and monitoring their potential effects on diagnosis, therapeutics, and vaccines by genomic sequencing is essential to manage global public crises. In the current study, spike-genome next-generation sequencing was generated from 492 SARS-CoV-2 isolates to evaluate the mutations in Turkey from April 2021 to February 2022. The variant analysis was performed using (Coronavirus Antiviral and Resistance Database (CoV-RDB) by Stanford University). We revealed that the lineages Alpha (B.1.1.7), Beta (B.1.351), Delta (B.1.617.2), Eta (B.1.525), variant of interest (VOI), lota (B.1.526), Zeta (P.2), Omicron (B.1.1.529), and Omicron BA.1 (B.1.1.529.1) were in the circulation in Turkey during the given period. The most common lineages were B.1.1.7, B.1.617.2, B.1.1.529, and B.1.1.529.1 SARS-CoV-2 variant circulation in Turkey seems highly heterogenetic; however, quite similar to the global epidemiologic analysis. The existence of globally circulating variants in the same chronological order in Turkey can be a guide for precautions, treatment, and vaccine options to be taken in the future.http://dx.doi.org/10.1155/2022/4677720
spellingShingle Murat Sayan
Ayse Arikan
Murat Isbilen
Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
Canadian Journal of Infectious Diseases and Medical Microbiology
title Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
title_full Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
title_fullStr Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
title_full_unstemmed Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
title_short Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey
title_sort circulating dynamics of sars cov 2 variants between april 2021 and february 2022 in turkey
url http://dx.doi.org/10.1155/2022/4677720
work_keys_str_mv AT muratsayan circulatingdynamicsofsarscov2variantsbetweenapril2021andfebruary2022inturkey
AT aysearikan circulatingdynamicsofsarscov2variantsbetweenapril2021andfebruary2022inturkey
AT muratisbilen circulatingdynamicsofsarscov2variantsbetweenapril2021andfebruary2022inturkey