Identification of novel therapeutic targets for cognitive performance and associations with brain health

Abstract Cognitive dysfunction poses a significant challenge in clinical practice, but currently available drugs mainly address symptoms and have limited effectiveness in treating cognitive dysfunction associated with various neurological disorders. Mendelian randomization (MR) and colocalization an...

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Bibliographic Details
Main Authors: Lu-Yang Zhang, Yu-Xin Liu, Yun-Hui Chu, Yun-Fan You, Luo-Qi Zhou, Sheng Yang, Ming-Hao Dong, Hang Zhang, Xiao-Wei Pang, Lian Chen, Li-Fang Zhu, Jun Xiao, Ke Shang, Wei Wang, Chuan Qin, Dai-Shi Tian
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03437-w
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