B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort

B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort

RationaleCigarette smoking (CS) impairs B-cell function and antibody production, increasing infection risk. The impact of e-cigarette use ('vaping') and combined CS and vaping ('dual-use') on B-cell activity is unclear.ObjectiveTo examine B-cell receptor sequencing (BCR-seq) prof...

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Bibliographic Details
Main Authors: Matthew Moll, Zhonghui Xu, Adel Boueiz, Min Hyung Ryu, Edwin K. Silverman, Michael H. Cho, Craig P. Hersh, Maor Sauler, Francesca Polverino, Gregory L. Kinney, Jeffrey L. Curtis, Laura E. Crotty-Alexander, Christopher Vollmers, Peter J. Castaldi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
COPD
B cell
immune repertoire
vaping
smoking
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1508786/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1508786/full

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