Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design

Objective Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). When approved by the Food and Drug Administration (FDA) in 1988, a maximum daily dosage limit of 800 mg (eight tablets) of the 25/100 ca...

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Bibliographic Details
Main Authors: Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson
Format: Article
Language:English
Published: BMJ Publishing Group 2012-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/2/6/e001971.full
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