Frequency of microsatellite instability in gynecologic cancers and the efficacy of immune checkpoint inhibitors treated: real-world data from a single gynecologic center

Frequency of microsatellite instability in gynecologic cancers and the efficacy of immune checkpoint inhibitors treated: real-world data from a single gynecologic center

ObjectiveThis study evaluated the incidence of Microsatellite Instability-High (MSI-H) in patients with gynecologic cancers in a single gynecologic center and investigated the effect of immune checkpoint inhibitors (ICIs) in treating MSI-H in advanced or recurrent gynecologic cancers.MethodsWe condu...

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Bibliographic Details
Main Authors: Wei Kuang, Jing Zeng, Lingling Tong, Qianqi Liu, Huanxin Sun, Min Feng, Dongni Liang, Wei Wang, Cheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
microsatellite instability
gynecologic cancers
immunotherapy
immune checkpoint inhibitors (ICIs)
objective response rate (ORR)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567824/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567824/full

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