Synthesis and application of a photocaged-l-lactate for studying the biological roles of l-lactate

Abstract l-Lactate, once considered a metabolic waste product of glycolysis, is now recognized as a vitally important metabolite and signaling molecule in multiple biological pathways. However, exploring l-lactate’s emerging intra- and extra-cellular roles is hindered by a lack of tools to perturb l...

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Bibliographic Details
Main Authors: Ikumi Miyazaki, Kelvin K. Tsao, Yuki Kamijo, Yusuke Nasu, Takuya Terai, Robert E. Campbell
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01495-1
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