Advances in dorzolamide hydrochloride delivery: harnessing nanotechnology for enhanced ocular drug delivery in glaucoma management

Abstract Dorzolamide hydrochloride (DRZ) is a carbonic anhydrase inhibitor utilized in managing elevated intraocular pressure (IOP) associated with glaucoma. However, its clinical effectiveness is hindered by a short half-life, low residence time, and the need for frequent dosing, highlighting the n...

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Bibliographic Details
Main Authors: Sagar R. Pardeshi, Amol D. Gholap, Navnath T. Hatvate, Khushmita D. Gharat, Jitendra B. Naik, Abdelwahab Omri
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Nano
Subjects:
Online Access:https://doi.org/10.1186/s11671-024-04154-x
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