Mechanosensor YAP mediates bone remodeling via NF-κB p65 induced osteoclastogenesis during orthodontic tooth movement

Mechanosensor YAP mediates bone remodeling via NF-κB p65 induced osteoclastogenesis during orthodontic tooth movement

Abstract Background Yes-associated protein (YAP) is a crucial mechanosensor involved in mechanotransduction, but its role in regulating mechanical force-induced bone remodeling during orthodontic tooth movement (OTM) is unclear. This study aims to elucidate the relationship between mechanotransducti...

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Main Authors: Jie Deng, Yu-Ning Zhang, Ru-Shui Bai, Ting-Ting Yu, Yi Zhao, Hao Liu, Yun-Fan Zhang, Tian-Min Xu, Bing Han
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Progress in Orthodontics
Subjects:
Yes-associated protein
Orthodontic tooth movement
Mechanotransduction
Bone remodeling
Osteoclast
NF-κB pathway
Online Access:https://doi.org/10.1186/s40510-024-00548-w
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https://doi.org/10.1186/s40510-024-00548-w

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