Progress in GABAA receptor agonists for insomnia disorder

Progress in GABAA receptor agonists for insomnia disorder

Insomnia is the most common sleep disorder in which an individual has trouble falling or staying asleep. Chronic sleep loss interferes with daily functioning and adversely affects health. The main clinical drugs for insomnia are the positive allosteric modulator of the GABA (gamma-aminobutyric acid)...

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Bibliographic Details
Main Authors: Weiyi Wang, Wanting Fu, Hongyan Zhu, Jing Ma, Jian Zhang, Jia Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
insomnia
GABAA receptor
benzodiazepines binding site
dimdazenil
partial positive allosteric modulator
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1432726/full
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