Uterine Repair Mechanisms Are Potentiated by Mesenchymal Stem Cells and Decellularized Tissue Grafts Through Elevated <i>Vegf</i>, <i>Cd44</i>, and <i>Itgb1</i> Gene Expression

Uterine Repair Mechanisms Are Potentiated by Mesenchymal Stem Cells and Decellularized Tissue Grafts Through Elevated <i>Vegf</i>, <i>Cd44</i>, and <i>Itgb1</i> Gene Expression

Transplantation of decellularized uterus tissue showed promise in supporting regeneration following uterine injury in animal models, suggesting an alternative to complete uterus transplantation for uterine factor infertility treatment. However, most animal studies utilized small grafts, limiting the...

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Main Authors: Sara Bandstein, Lucia De Miguel-Gómez, Edina Sehic, Emy Thorén, Sara López-Martínez, Irene Cervelló, Randa Akouri, Mihai Oltean, Mats Brännström, Mats Hellström
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
uterus factor infertility
bioengineering
decellularized scaffolds
mesenchymal stem cells
infertility
uterus transplantation
Online Access:https://www.mdpi.com/2306-5354/11/12/1268
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