Microglial polarization pathways and therapeutic drugs targeting activated microglia in traumatic brain injury

Microglial polarization pathways and therapeutic drugs targeting activated microglia in traumatic brain injury

Traumatic brain injury can be categorized into primary and secondary injuries. Secondary injuries are the main cause of disability following traumatic brain injury, which involves a complex multicellular cascade. Microglia play an important role in secondary injury and can be activated in response t...

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Bibliographic Details
Main Authors: Liping Shi, Shuyi Liu, Jialing Chen, Hong Wang, Zhengbo Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-01-01
Series:Neural Regeneration Research
Subjects:
animal model
anti-inflammatory drug
cell replacement strategy
central nervous system
mesenchymal stem cell
microglia
neuroinflammation
non-human primate
signaling pathway
traumatic brain injury
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00810
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https://journals.lww.com/10.4103/NRR.NRR-D-24-00810

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