Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis

Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis

Radiotherapy is a method of treating cancer through radiation aimed at killing cancer cells or inhibiting their growth. However, radiotherapy has numerous side effects because it kills tumors while causing damage to normal cells or tissues. The literature shows that radiation can cause damage to hea...

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Main Authors: Jiahao Wu, Kaihua Ji, Guangbo Kang, Manman Zhang, Jigang Wang, Lina Wang, Mengxue Gao, Xiaoxiao Jia, Xinran Lu, Yan Wang, Xinran Gao, Yufei Guo, Zhixin Zhu, Qinghua Wang, Zhenyu Zhao, Qiang Liu, He Huang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research
Subjects:
Radiation
Butyrate
Gut
Heart
Gut microbiota
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825000672
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