Gemcitabine: immunomodulatory or immunosuppressive role in the tumor microenvironment

Gemcitabine (GEM), a nucleoside analog chemotherapy agent, has been widely used in the treatment of various cancers. In recent years, there has been growing interest in understanding the immunomodulatory or immunosuppressive effects of GEM. The immunomodulatory roles of GEM could influence the anti-...

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Bibliographic Details
Main Authors: Mahnaz Nemati, Chou-Yi Hsu, Deepak Nathiya, M. Ravi Kumar, Enwa Felix Oghenemaro, Muthena Kariem, Parjinder Kaur, Deepak Bhanot, Ahmed Hjazi, Tayebeh Azam Saedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1536428/full
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