Aggressive serous ovarian cancer subtype defined by high centrality lncRNA profiles and master transcription factors

Aggressive serous ovarian cancer subtype defined by high centrality lncRNA profiles and master transcription factors

Abstract Long non-coding RNAs (lncRNAs) regulate the progression and metastasis of high-grade serous carcinoma ovarian cancer (HGSC). However, HGSC is yet to be classified based on these transcripts. In addition, the crosstalk between master transcriptional factors (MTFs) and lncRNAs remains unclear...

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Bibliographic Details
Main Authors: Seonhyang Jeong, Young Suk Jo, Sunmi Park, Hwayoung Lee, Eun Gyeong Park, Sang Geun Jung, Jandee Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Ovarian cancer
High-grade serous ovarian cancer
Long Noncoding RNA
Biomarker
Multi-omics data
Online Access:https://doi.org/10.1038/s41598-025-06262-9
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https://doi.org/10.1038/s41598-025-06262-9

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