Free fatty acid-induced DDX3 inhibits autophagy via miR-141 upregulation in diet-induced MASLD mice model system

Free fatty acid-induced DDX3 inhibits autophagy via miR-141 upregulation in diet-induced MASLD mice model system

Introduction and Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the primary causes of chronic liver disease and may lead to liver cirrhosis and hepatocellular carcinoma. Recent reports suggested that DEAD-box RNA helicase (DDX3) acts as a sensor of free fat ac...

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Main Authors: Md. Musa Hossain, Amit K. Mishra, Ajay K. Yadav, Md. Ismail, Teja Naveen Sata, Amrendra K. Sah, Arnab Banik, Gopal Sharma, Senthil K. Venugopal
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Annals of Hepatology
Subjects:
MASLD
DDX3
CDAA diet fed mice
miR-141
Sirt-1
autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268124005416
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http://www.sciencedirect.com/science/article/pii/S1665268124005416

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