Recent Trends and Future Directions in 3D Printing of Biocompatible Polymers

Recent Trends and Future Directions in 3D Printing of Biocompatible Polymers

Three-dimensional (3D) bioprinting using biocompatible polymers has emerged as a revolutionary technique in tissue engineering and regenerative medicine. These biopolymers mimic the extracellular matrix (ECM) and enhance cellular behavior. The current review presents recent advancements in additive...

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Main Authors: Maryam Aftab, Sania Ikram, Muneeb Ullah, Niyamat Khan, Muhammad Naeem, Muhammad Amir Khan, Rakhmonov Bakhrombek Bakhtiyor o’g’li, Kamalova Sayyorakhon Salokhiddin Qizi, Oribjonov Otabek Erkinjon Ugli, Bekkulova Mokhigul Abdurasulovna, Oribjonova Khadisakhon Abdumutallib Qizi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Journal of Manufacturing and Materials Processing
Subjects:
3D bioprinting
extracellular matrix
biopolymers
stereolithography
fused deposition modeling
selective laser sintering
Online Access:https://www.mdpi.com/2504-4494/9/4/129
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Summary:Three-dimensional (3D) bioprinting using biocompatible polymers has emerged as a revolutionary technique in tissue engineering and regenerative medicine. These biopolymers mimic the extracellular matrix (ECM) and enhance cellular behavior. The current review presents recent advancements in additive manufacturing processes including Stereolithography (SLA), Fused Filament Fabrication (FFF), Selective Laser Sintering (SLS), and inkjet printing. It also explores the fundamentals of 3D printing and the properties of biocompatible polymers for 3D bioprinting. By mixing biopolymers, enhancing rheological characteristics, and adding bioactive components, further advancements have been made for organ transplantation, drug development, and tissue engineering. As research progresses, the potential for 3D bioprinting to fundamentally transform the healthcare system is becoming obvious and clear. However, the therapeutic potential of printed structures is hindered by issues such as material anisotropy, poor mechanical properties, and the need for more biocompatible and biodegradable architectures. Future research should concentrate on optimizing the 3D bioprinting process using sophisticated computational techniques, systematically examining the characteristics of biopolymers, customizing bioinks for different cell types, and exploring sustainable materials.
ISSN:2504-4494

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