Bidirectional two-sample Mendelian randomization analysis identifies protein C rather than protein S or antithrombin-III as associated with deep venous thrombosis

Bidirectional two-sample Mendelian randomization analysis identifies protein C rather than protein S or antithrombin-III as associated with deep venous thrombosis

Introduction Observational studies have indicated significant contributions of protein C and protein S to thrombotic diseases, yet the “anticoagulation paradox” in deep venous thrombosis (DVT) remains unresolved. Therefore, we conducted an investigation to discern the causal effects of protein C, pr...

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Bibliographic Details
Main Authors: Liang Shu, Liyan Sun, Cong Yu, Dabin Ren, Yisong Zhang, Ping Zheng
Format: Article
Language:English
Published: Termedia Publishing House 2024-06-01
Series:Archives of Medical Science
Subjects:
protein c
deep venous thrombosis
causal effect
mendelian randomization
mediating effect
Online Access:https://www.archivesofmedicalscience.com/Bidirectional-two-sample-Mendelian-randomization-analysis-identifies-protein-C-rather,188205,0,2.html
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