An online tool for fetal fraction prediction based on direct size distribution analysis of maternal cell-free DNA

The discovery of circulating fetal DNA in the plasma of pregnant women has greatly promoted advances in noninvasive prenatal testing. Screening performance is enhanced with higher fetal fraction and analysis of samples whose fetal DNA fraction is lower than 4% are unreliable. Although current approa...

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Bibliographic Details
Main Authors: Luca Bedon, Josef Vuch, Simeone Dal Monego, Germana Meroni, Vanna Pecile, Danilo Licastro
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/btn-2020-0143
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