Hybrid IgE-IgG1 antibodies (IgEG): a new antibody class that combines IgE and IgG functionality

IgG-based anti-cancer therapies have achieved promising clinical outcomes, but, especially for patients with solid tumors, response rates vary. IgE antibodies promote distinct immune responses compared to IgG and have shown anti-tumoral pre-clinical activity and preliminary efficacy and safety profi...

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Bibliographic Details
Main Authors: Melanie Grandits, Lais C. G. F. Palhares, Olivia Macleod, John Devlin, Oliver E. Amin, James Birtley, Leanne Partington, Tim Wilson, Elizabeth Hardaker, Sophia N. Karagiannis, Heather J. Bax, Kevin FitzGerald
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
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Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2502673
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