Risk Factors for Radiation-Induced Keratoconjunctivitis Sicca in Dogs Treated with Hypofractionated Intensity-Modulated Radiation Therapy for Intranasal Tumors

Risk Factors for Radiation-Induced Keratoconjunctivitis Sicca in Dogs Treated with Hypofractionated Intensity-Modulated Radiation Therapy for Intranasal Tumors

Radiation-induced keratoconjunctivitis sicca (KCS) is a significant late complication in dogs receiving radiation therapy for intranasal tumors, particularly with hypofractionated intensity-modulated radiation therapy (IMRT). This retrospective case-control study was performed to identify anatomical...

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Bibliographic Details
Main Authors: Akihiro Ohnishi, Soichirou Takeda, Yoshiki Okada, Manami Tokoro, Saki Kageyama, Yoshiki Itoh, Taketoshi Asanuma
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Animals
Subjects:
keratoconjunctivitis sicca
canine intranasal tumor
intensity-modulated radiation therapy
dosimetric analysis
radiation-induced ocular toxicity
dose threshold
Online Access:https://www.mdpi.com/2076-2615/15/15/2258
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