Prognostic role of eIF2α protein in metastatic renal cell cancer patients

Prognostic role of eIF2α protein in metastatic renal cell cancer patients

Abstract Background One of the major dilemmas in the treatment of renal cell carcinoma (RCC) is the resistance to therapy that leads to a state of unresponsiveness, which is observed after a certain period. Among the potential causes of this, the impact of autophagy activation and the resulting endo...

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Main Authors: Ferhat Ekinci, Hanife Seda Mavili, Nalan Neşe, Atike Pınar Erdoğan, Bilgin Demir, Esin Oktay, Nil Çulhacı, Mehmet Uzun, Aziz Karaoğlu, Kutsal Yörükoğlu, Emine Burçin Tuna, Ahmet Dirican
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Renal cell carcinoma
Autophagy
Endoplasmic reticulum stress
eIF2α
Online Access:https://doi.org/10.1007/s12672-025-02916-2
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https://doi.org/10.1007/s12672-025-02916-2

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