Efficacy of artemisinin-based combination therapy (ACT) in people living with HIV (PLHIV) diagnosed with uncomplicated Plasmodium falciparum malaria in Africa: a WWARN systematic review

Efficacy of artemisinin-based combination therapy (ACT) in people living with HIV (PLHIV) diagnosed with uncomplicated Plasmodium falciparum malaria in Africa: a WWARN systematic review

Abstract Background Africa bears the highest double burden of HIV and malaria worldwide. In 2023, an estimated 25.9 million people were living with HIV (PLHIV), and 246 million malaria cases were diagnosed in Africa. Malaria patients co-infected with HIV are considered at a higher risk of failing ma...

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Main Authors: Abena Takyi, Aboubakar Soma, Marianna Przybylska, Eli Harriss, Karen I. Barnes, Prabin Dahal, Philippe J. Guérin, Kasia Stepniewska, Verena I. Carrara
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Malaria Journal
Subjects:
Human immunodeficiency virus
Anti-retroviral drugs
People living with HIV
Artemisinin-based combination therapy
Malaria
Drug-drug interactions
Online Access:https://doi.org/10.1186/s12936-025-05393-8
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https://doi.org/10.1186/s12936-025-05393-8

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