Tissue-specific effects of bacterial PncA overexpression on NAD+ metabolism and aging in mice: implications for tissue-specific aging interventions

Tissue-specific effects of bacterial PncA overexpression on NAD+ metabolism and aging in mice: implications for tissue-specific aging interventions

BackgroundAs a critical molecule in biological systems, nicotinamide adenine dinucleotide (NAD+) influences the aging of mammals. Therefore, regulation of NAD+ synthesis and degradation may slow aging and mitigate related diseases.ResultsThis study investigated how mammalian tissues rely on differen...

Full description

Saved in:
Bibliographic Details
Main Authors: Fengjiao Huo, Meili Zhao, Yue Liu, Shuyao Lv, Shengyu Feng, Liuling Guo, Nan Wang, Shuaishuai Zhang, Qing Liu, Taotao Mi, Hao Wang, Jian-Kang Zhu, Hailiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Aging
Subjects:
aging
nicotinamide adenine dinucleotide
nicotinamide
nicotinic acid
pncA
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2025.1546017/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fragi.2025.1546017/full

Similar Items