Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast.

Glucose is the preferred carbon and energy source in prokaryotes, unicellular eukaryotes, and metazoans. However, excess of glucose has been associated with several diseases, including diabetes and the less understood process of aging. On the contrary, limiting glucose (i.e., calorie restriction) sl...

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Bibliographic Details
Main Authors: Antoine E Roux, Alexandre Leroux, Manal A Alaamery, Charles S Hoffman, Pascal Chartrand, Gerardo Ferbeyre, Luis A Rokeach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000408&type=printable
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