Mitochondrial DNA depletion syndrome and its cardiac complication

Mitochondrial depletion syndrome (MTDPS) is a heterogeneous group of genetic disorders characterized by a significant reduction in mitochondrial DNA (mtDNA) copy number, leading to the impaired mitochondrial function. The pathogenesis of MTDPS includes impaired mtDNA replication, damaged nucleotide...

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Bibliographic Details
Main Authors: Shengfang Bao, Jiajun Ye, Jiaqi Zhou, Chen Zheng, Yuejuan Xu, Sun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1582219/full
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