Exploring novel blood-based DNA methylation biomarkers for alzheimer’s disease via targeted sequencing of highly variable CpG sites

Abstract Objective Dementia, particularly Alzheimer’s disease (AD), continues to be a major public health concern due to population aging, yet minimally invasive biomarkers for early diagnosis have not been established. DNA methylation (DNAm) has recently attracted considerable attention as a promis...

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Bibliographic Details
Main Authors: Hideki Ohmomo, Shohei Komaki, Shiori Minabe, Yoichi Sutoh, Yayoi Otsuka-Yamasaki, Makoto Sasaki, Atsushi Shimizu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Research Notes
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Online Access:https://doi.org/10.1186/s13104-025-07417-7
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