Endocytosis of Wnt ligands from surrounding epithelial cells positions microtubule nucleation sites at dendrite branch points.

Microtubule nucleation is important for microtubule organization in dendrites and for neuronal injury responses. The core nucleation protein, γTubulin (γTub), is localized to dendrite branch points in Drosophila sensory neurons by Wnt receptors and scaffolding proteins on endosomes. However, whether...

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Bibliographic Details
Main Authors: Pankajam Thyagarajan, Hannah S Mirshahi, Gregory O Kothe, Nitish Kumar, Melissa Long, Bowofoluwa S Abimbola, Alexis T Weiner, Melissa M Rolls
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002973
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