C‐type natriuretic peptide induces inotropic and lusitropic effects in human 3D‐engineered cardiac tissue: Implications for the regulation of cardiac function in humans

C‐type natriuretic peptide induces inotropic and lusitropic effects in human 3D‐engineered cardiac tissue: Implications for the regulation of cardiac function in humans

Abstract The role of C‐type natriuretic peptide (CNP) in the regulation of cardiac function in humans remains to be established as previous investigations have been confined to animal model systems. Here, we used well‐characterized engineered cardiac tissues (ECTs) generated from human stem cell‐der...

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Bibliographic Details
Main Authors: Julian C. Bachmann, Jeppe E. Kirchhoff, Julia E. Napolitano, Steve Sorota, William M. Gordon, Nicole Feric, Roozbeh Aschar‐Sobbi, Juan Lv, Zhiyou Cao, Ken Coppieters, Giulia Borghetti, Michael Nyberg
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Experimental Physiology
Subjects:
contractility
human stem cell‐derived cardiomyocytes
Langendorff isolated heart
relaxation
translation
Online Access:https://doi.org/10.1113/EP091303
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https://doi.org/10.1113/EP091303

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