Immunoinformatics approach for design novel multi-epitope prophylactic and therapeutic vaccine based on capsid proteins L1 and L2 and oncoproteins E6 and E7 of human papillomavirus 16 and human papillomavirus 18 against cervical cancer

Immunoinformatics approach for design novel multi-epitope prophylactic and therapeutic vaccine based on capsid proteins L1 and L2 and oncoproteins E6 and E7 of human papillomavirus 16 and human papillomavirus 18 against cervical cancer

Objectives This study aimed to identify the optimal protein construction for designing a multi-epitope vaccine with both prophylactic and therapeutic effects against cervical cancer, utilizing an immunoinformatics approach. The construction process involved using capsid epitopes L1 and L2, as well a...

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Bibliographic Details
Main Authors: Nicholas Ryan, Sari Eka Pratiwi, Mardhia Mardhia, Ysrafil Ysrafil, Delima Fajar Liana, Mahyarudin Mahyarudin
Format: Article
Language:English
Published: Korea Disease Control and Prevention Agency 2024-08-01
Series:Osong Public Health and Research Perspectives
Subjects:
antigenic epitopes
human papillomavirus viruses
immunoinformatics
prevention
therapeutics
uterine cervical neoplasms
Online Access:http://ophrp.org/upload/pdf/j-phrp-2024-0013.pdf
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http://ophrp.org/upload/pdf/j-phrp-2024-0013.pdf

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