Unraveling the nexus: Genomic instability and metabolism in cancer

Summary: The DNA-damage response (DDR) is a signaling network that enables cells to detect and repair genomic damage. Over the past three decades, inhibiting DDR has proven to be an effective cancer therapeutic strategy. Although cancer drugs targeting DDR have received approval for treating various...

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Bibliographic Details
Main Authors: Vaibhavi Gujar, Haojian Li, Tanya T. Paull, Carola A. Neumann, Urbain Weyemi
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003110
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