Cell viability measured by cytotoxicity assay as a biomarker of chronic obstructive pulmonary disease exacerbation: a prospective cohort study

Cell viability measured by cytotoxicity assay as a biomarker of chronic obstructive pulmonary disease exacerbation: a prospective cohort study

Abstract Acute severe exacerbation of chronic obstructive pulmonary disease (COPD) is related to high mortality; however, a robust blood biomarker for COPD exacerbation has not been established. Impaired clearance of apoptotic cells is a possible pathogenesis of COPD development. We evaluated the cl...

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Main Authors: Ye Jin Lee, Eun-Young Eo, Dong Hyun Joo, Si-mong Yoon, Hyung-Jun Kim, Myung Jin Song, Byoung Soo Kwon, Yeon Wook Kim, Sung Yoon Lim, Yeon-Joo Lee, Jong Sun Park, Young-Jae Cho, Jae Ho Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Cell viability
Chronic obstructive pulmonary disease
Exacerbation
Lactate dehydrogenase cytotoxicity assay
Online Access:https://doi.org/10.1038/s41598-025-14536-5
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https://doi.org/10.1038/s41598-025-14536-5

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