Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report

Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report

IntroductionAcute hemorrhagic leukoencephalitis (AHLE) is a rare, fulminant neuroinflammatory disease with high mortality rate. It most often occurs after infections; however, the exact etiology of the disease remains unclear. We highlight that complement factor I (FI) deficiency may be a possible c...

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Main Authors: Fanni Szumutku, Léna Szabó, Zoltán Liptai, Edit Varga, Tímea Seszták, Péter Barsi, Ádám Goschler, Gábor Szarvas, Klára Horváth, Simon Péter Nagy, Zoltán Prohászka, Ágnes Szilágyi, Sarolta Dobner
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
acute hemorrhagic leukoencephalitis
complement factor I deficiency
neuroinflammatory disease
immune-mediated neurological disorder
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1586288/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1586288/full

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