Release of prostaglandin D2 by murine mast cells: importance of metabolite formation for antiproliferative activity
Prostaglandin (PG) D2 , PGJ2 and Δ12 -PGJ2 are antiproliferative eicosanoids. We investigated the production of PGD2 by murine bone marrow-derived mast cells (BMMC) taking into consideration metabolism of PGD2 to PGD2 and Δ12-PGJ2. PG-metabolites were quantified by high performance liquid chromatogr...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
1998-01-01
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Series: | Mediators of Inflammation |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09629359891216 |
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