Acteoside ameliorates hepatocyte ferroptosis and hepatic ischemia-reperfusion injury via targeting PCBP2

Acteoside ameliorates hepatocyte ferroptosis and hepatic ischemia-reperfusion injury via targeting PCBP2

Hepatic ischemia-reperfusion injury (HIRI) has been considered as an inevitable process of liver transplantation. Hepatocyte ferroptosis is a key factor in HIRI development, yet precise mechanism and potential therapies are still unclear. Here, we demonstrated a strong correlation between hepatocyte...

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Bibliographic Details
Main Authors: Kexin Jia, Yinhao Zhang, Fanghong Li, Runping Liu, Jianzhi Wu, Jiaorong Qu, Ranyi Luo, Zixi Huang, Zhe Xu, Xiaojiaoyang Li
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Acteoside
Hepatic ischemia–reperfusion injury
Ferroptosis
PCBP2
System Xc–
HMGB1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525001194
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