Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis

Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis

Summary: Mitotic chromosomes oscillate between the spindle poles upon the establishment of bi-orientation, which is essential for chromosome alignment and subsequent synchronous segregation. However, the molecular mechanisms underlying the oscillatory movement remain unclear. Recent studies revealed...

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Main Authors: Chengcheng Hu, Qing Hu, Tongtong Yang, Panpan Xu, Fangyuan Xiong, Xinyang Wang, Chao Wang, Kai Jiang, Donald L. Hill, Lin Xue, Changlu Tao, Chuanhai Fu, Liang Zhang, Dan Liu, Shengqi Xiang, Jianye Zang, Zhikai Wang, Xuebiao Yao, Xing Liu
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003316
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