Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration

Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration

Background: Internal ocular diseases, such as macular edema, uveitis, and diabetic macular edema require precise delivery of therapeutic agents to specific regions within the eye. However, the eye’s complex anatomical structure and physiological barriers present significant challenges to drug penetr...

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Bibliographic Details
Main Authors: Sa Huang, Yuan Xu, Yingyao Luo, Zhijiong Wang, Fan Li, Zhenmiao Qin, Junfeng Ban
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
ocular drug delivery
nanoparticles
cell-penetrating peptides
PLGA
pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/16/12/1496
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