Cerebroprotective effect of sitagliptin and aminoguanidine combination in disorders of cerebral circulation

Cerebroprotective effect of sitagliptin and aminoguanidine combination in disorders of cerebral circulation

The aim of the study was to evaluate a cerebroprotective activity of the sitagliptin and aminoguanidine combination in rats with an acute and chronic cerebral circulation insufficiency, as well as with a traumatic brain injury.Materials and methods. The study was carried out on male Wistar rats in 3...

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Main Authors: D. V. Kurkin, D. A. Bakulin, E. I. Morkovin, Yu. V. Gorbunova, A. V. Strygin, T. M. Andriashvili, A. A. Sokolova, N. S. Bolokhov, V. E. Pustynnikov, E. A. Fomichev, A. V. Baskova, S. S. Polodyants, A. V. Kasparova
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2023-08-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
dpp-4 inhibitors
sitagliptin
preclinical studies
acute and chronic cerebral circulation insufficiency
traumatic brain injury
Online Access:https://www.pharmpharm.ru/jour/article/view/1295
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