GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem

GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem

Objective: Growth differentiation factor 15 (GDF15) acts on the receptor dimer of GDNF family receptor alpha-like (GFRAL) and Rearranged during transfection (RET). While Gfral-expressing cells are known to be present in the area postrema and nucleus of the solitary tract (AP/NTS) located in the brai...

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Bibliographic Details
Main Authors: Cecilia Hes, Lu Ting Gui, Alexandre Bay, Fernando Alvarez, Pierce Katz, Tanushree Paul, Nadejda Bozadjieva-Kramer, Randy J. Seeley, Ciriaco A. Piccirillo, Paul V. Sabatini
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Molecular Metabolism
Subjects:
GDF15
GFRAL
Area postrema
Nucleus of the solitary tract
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824002011
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http://www.sciencedirect.com/science/article/pii/S2212877824002011

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