Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes

2-Phenyl-6,7-difluoro and 2-(4-fluorophenyl)quinazoline derivatives bearing salicylidenhydrazino fragments at position 4 were prepared based on 4,5-difluoroantranilic acid or anthranilamide. Molecular docking to casein kinase 2 was performed; compounds with high in silico activity to CK2 were reveal...

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Main Authors: Emiliya V. Nosova, Ilya I. Butorin, Margarita D. Likhacheva, Svetlana K. Kotovskaya
Format: Article
Language:English
Published: Ural Federal University 2023-05-01
Series:Chimica Techno Acta
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Online Access:https://chimicatechnoacta.ru/article/view/6708
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