Characterizing microglial heterogeneity in autophagy impairment of Paraquat-induced Parkinson’s disease-like neurodegeneration

Characterizing microglial heterogeneity in autophagy impairment of Paraquat-induced Parkinson’s disease-like neurodegeneration

Parkinson's disease (PD) is a prevalent neurodegenerative condition influenced by environmental elements, notably Paraquat (PQ), which is one of the known risk factors. Impaired autophagy is a critical factor in the pathogenesis of PD, yet the cellular heterogeneity related to autophagy in PD h...

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Bibliographic Details
Main Authors: Yu Zhang, Yihua Jiang, Zhen Yu, Yinhan Li, Zhiyu Zhang, Fuli Zheng, Hong Hu, Guangxia Yu, Zhenkun Guo, Siying Wu, Wenya Shao, Huangyuan Li
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Paraquat
Single-cell transcriptomics
Parkinson’s disease
Autophagy
Microglia
Cell heterogeneity
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325007006
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