Modeling the effects of radiation on the bone tumor microenvironment: opportunities for exploring combination therapies in microphysiologic systems

Abstract Primary bone tumors and bone metastases represent significant challenges in oncology. Radiotherapy is an important adjuvant treatment for several primary bone and musculoskeletal tumors, as well as for palliative care for metastatic bone lesions. While effective in these applications, patie...

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Bibliographic Details
Main Authors: Kailey N. Jackett, Devin L. DaPonte, Pranav Soman, Jason A. Horton
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cellular & Molecular Biology Letters
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Online Access:https://doi.org/10.1186/s11658-025-00774-y
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