Cordycepin pretreatment inhibits the release of CCL2 by mesenchymal stem cells and protects renal tubular epithelial cells from apoptosis.

Cordycepin pretreatment inhibits the release of CCL2 by mesenchymal stem cells and protects renal tubular epithelial cells from apoptosis.

ObjectiveInvestigate whether the pretreatment with cordycepin can protect the renal tubular epithelial cells （HK-2 cells） from cell death induced by hypoxia/reoxygenation （H/R）.MethodsObtain the targets of stem cell therapy for AKI from the GEO （GSE84563） database. Obtain the targets of cordycepin r...

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Bibliographic Details
Main Authors: Chen Fa-hui, Zhao Zhi-bo, Bai Meng-qi, Li Jun-hu, Ren Xi-ya, Zhao Li-mei, Hao Ya-jie, Song Hong, Wang Xiao-ju, Zhou Xiao-shuang
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2025-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Acute kidney injury
Cordycepin
Mesenchymal stem cells
CCL2
Apoptosis
Online Access:http://www.lcszb.com/thesisDetails?columnId=104539727&Fpath=home&index=0
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