Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials

Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials

Abstract Introduction Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower doses, thereby aiding tolerability. Co-crystal of tramadol-celecoxib (CTC) provides effective analgesia in models of acute pain. Co-crystallization can alter...

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Bibliographic Details
Main Authors: Eugene R. Viscusi, Richard Langford, Adelaida Morte, Anna Vaqué, Jesús Cebrecos, Mariano Sust, José María Giménez-Arnau, Oscar de Leon-Casasola
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-09-01
Series:Pain and Therapy
Subjects:
Acute pain
Analgesia
Analgesics
Opioid
Pain
Postoperative
Online Access:https://doi.org/10.1007/s40122-024-00655-w
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https://doi.org/10.1007/s40122-024-00655-w

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