Assessing the predictive efficacy of European-based systolic blood pressure polygenic risk scores in diverse Brazilian cohorts
Abstract Despite the identification of numerous genetic variants affecting SBP in European populations, their applicability in admixed populations remains unclear. This study evaluates the predictive efficacy of a systolic blood pressure (SBP) polygenic risk score (PRS), derived from the UK Biobank...
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Main Authors: | Samantha K. Teixeira, Fernando P. N. Rossi, José L. Patane, Jennifer M. Neyra, Ana Vitória V. Jensen, Bernardo L. Horta, Alexandre C. Pereira, Jose E. Krieger |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-79683-7 |
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